Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is Kansas City (70% of total searches to Missouri). The next most popular destinations are Half Way (11%) and West Plains (11%). Searches for hotels in Branson (7%) are also popular.
KAYAK users have found double rooms in Missouri for as cheap as $46 (St. Louis) in the last 3 days. The average price is $295.